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Breast cancer tumors aren’t the same throughout

Not only is breast cancer more than one disease, but a single breast cancer tumor can also differ depending on where you look. This means that tumor-sampling techniques used with “personalized...

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Tumors use local food shortage against T-cells

The microenvironment that supports a cancerous tumor also starves the immune cells the body sends in to destroy the cancer, scientists report. The finding holds the potential to significantly boost the...

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Why doctors need to check breast cancer for mutations

A new breast cancer study shows that tumors can mutate in response to treatments that reduce estrogen levels in the body. While estrogen-lowering drugs are often effective in reducing tumor size,...

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One gene links autism and tumor disorder

Scientists have linked mutations in a single gene to autism in people who have a rare tumor syndrome typically diagnosed in childhood. The findings, in patients with neurofibromatosis type 1 (NF1), may...

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‘Toothy’ tumor found in this prehistoric animal’s mouth

Scientists have discovered an odontoma tumor in the mouth of a creature that lived 225 million years ago. The tumors, which are made up of miniature toothlike structures, are common in mammals today....

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Hungry salmonella hunt and then eat brain tumors

A detoxified version of salmonella is proving to be an unlikely weapon for treating glioblastoma, the deadliest form of brain cancer. Glioblastoma is difficult to treat with drugs and nearly impossible...

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Using CRISPR against cancer shows success in mice

Using CRISPR to edit the “fusion genes” that can cause or worsen cancer reduced the size of tumors and improved survival in mice, report researchers. “This is the first time that gene editing has been...

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Targeting these T cells may let immune system kill cancer

Targeting a group of immune cells called regulatory T cells may be a way to boost the immune system’s response to tumors, a new study suggests. Immunotherapy drugs that push the immune system to detect...

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Microscope could test tumors during surgery

A new microscope can give surgeons real-time pathology data to guide cancer-removal surgeries and can also non-destructively examine tumor biopsies in 3D. When women undergo lumpectomies to remove...

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These molecules hitch a ride to destroy cancer

Researchers have found that a modified ribonucleic acid molecule can “hitchhike” on a plentiful human protein to travel through the blood to a tumor, and then signal that tumor to self-destruct. Their...

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Musician plays sax during surgery to remove brain tumor

Music teacher Dan Fabbio had a tumor in his brain—and in an area responsible for music function. His journey to recovery culminated with him awake and playing a saxophone as surgeons operated on his...

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Cortisol and serotonin linked to male liver cancer

Two hormone factors, cortisol and serotonin, play critical roles in the development of male-biased liver cancers, biologists report. Liver cancer occurs more frequently in males than females. This...

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Protein that enables and kills cancer could be new target

A protein called inositol-requiring enzyme 1, or IRE1, may play a key role in a series of molecular interactions that can both promote and, paradoxically, inhibit tumors in certain types of cancers,...

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Knocking out DNA repair system could boost chemo’s kick

Cells have a way of sensing the damage that certain chemotherapy drugs induce, researchers report. This finding could have important implications for treating cancer. The busy world inside a cell is...

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How cell ‘house cleaners’ boost prostate cancer

New research identifies the pathway by which the body’s natural process for removing dead and dying cells can actually fuel tumor growth, a little understood paradox of certain cancers. The finding...

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Test aims to detect tumors with tiny, light-up tubes

Researchers have refined and, for the first time, run in vivo tests of a method that may allow nanotube-based probes to locate specific tumors in the body. The new results suggest that...

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Light-up specks find and track tiny tumors

Scientists have created a method to detect tiny tumors and track their spread using light-emitting nanoparticles. “You can treat the tumors intelligently because now you know the address of the...

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Mice can mimic human breast cancer genes

Mice can mimic human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral, and esophagus, a new study suggests. Cancer is the second...

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Light acts as precision weapon to attack cancer

A new anti-cancer strategy goes beyond traditional light therapy—which is limited to the skin and areas accessible with an endoscope—to target and attack cancer cells that have spread deep inside the...

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‘Vaccine’ kills cancer in mice

Injecting small amounts of two immune-stimulating agents directly into solid tumors in mice eliminated all traces of cancer, including distant, untreated metastases, according to a new study. The...

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